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Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors
Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Schiaffino Ortega, Santiago; Chayah, Mariem; Kimatrai Salvador, Maria; Lopez-Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Mattiuzzo, Elena; Viola, Giampietro
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Contributo in rivista (Pubblicazione in Rivista) |
JOURNAL OF MEDICINAL CHEMISTRY
Vol. 62, No. 3, pp: 1274-1290, Anno: 2019 |
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A 2a adenosine receptor: Structures, modeling, and medicinal chemistry
Baraldi, S.; Baraldi, P. G.; Oliva, P.; Toti, K. S.; Ciancetta, A.; Jacobson, K. A.
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Contributo in volume |
Humana Press Inc.,
The Adenosine Receptors
Vol. 34, No. 1, pp: 91-136, Anno: 2018 |
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A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy
Jacobson, Ka; Merighi, Stefania; Varani, Katia; Borea, Pier Andrea; Baraldi, Stefania; AGHAZADEH TABRIZI, Mojgan; Romagnoli, Romeo; Baraldi, Pier Giovanni; Ciancetta, A; Tosh, Dk; Gao, Zg; Gessi, Stefania
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Contributo in rivista (Pubblicazione in Rivista) |
MEDICINAL RESEARCH REVIEWS
Vol. 38, No. 4, pp: 1031-1072, Anno: 2018 |
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Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells
Romagnoli, Romeo; Prencipe, Filippo; Lopez-Cara, Luisa Carlota; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Estévez-Sarmiento, Francisco; Quintana, José; Estévez, Francisco
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Contributo in rivista (Pubblicazione in Rivista) |
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Vol. 33, No. 1, pp: 727-742, Anno: 2018 |
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3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Bortolozzi, Roberta; Viola, Giampietro
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Contributo in rivista (Pubblicazione in Rivista) |
BIOORGANIC CHEMISTRY
Vol. 80, No. 1, pp: 361-374, Anno: 2018 |
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Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors
Aghazadeh Tabrizi, M.; Baraldi, P. G.; Baraldi, S.; Ruggiero, E.; De Stefano, L.; Rizzolio, F.; Di Cesare Mannelli, L.; Ghelardini, C.; Chicca, A.; Lapillo, M.; Gertsch, J.; Manera, C.; Macchia, M.; Martinelli, A.; Granchi, C.; Minutolo, F.; Tuccinardi, T.
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Contributo in rivista (Pubblicazione in Rivista) |
JOURNAL OF MEDICINAL CHEMISTRY
Vol. 61, No. 3, pp: 1340-1354, Anno: 2018 |
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Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents
Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Salvador, Maria Kimatrai; Lopez Cara, Luisa Carlota; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Porcù, Elena; Basso, Giuseppe; Viola, Giampietro
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Contributo in rivista (Pubblicazione in Rivista) |
SCIENTIFIC REPORTS
Vol. 7, No. 1, pp: 46356-1-46356-19, Anno: 2017 |
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Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents
Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Salvador, Maria Kimatrai; Lopez Cara, Luisa Carlota; Bortolozzi, Roberta; Mattiuzzo, Elena; Basso, Giuseppe; Viola, Giampietro
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Contributo in rivista (Pubblicazione in Rivista) |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Vol. 134, No. 1, pp: 258-270, Anno: 2017 |
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Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists
AGHAZADEH TABRIZI, Mojgan; Baraldi, Pier Giovanni; Baraldi, Stefania; Gessi, Stefania; Merighi, Stefania; Borea, Pier Andrea
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Contributo in rivista (Pubblicazione in Rivista) |
MEDICINAL RESEARCH REVIEWS
Vol. 37, No. 4, pp: 936-983, Anno: 2017 |
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Anti-cancer compounds
Balzarini, Jan; Dehaen, Wim; Thomas, Joice; Liekens, Sandra; Romagnoli, Romeo; Baraldi, Pier Giovanni
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Brevetto |
Anno: 2016 |
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Synthesis and Structure Activity Relationship Investigation of Triazolo[1,5-a]pyrimidines as CB2 Cannabinoid Receptor Inverse Agonists
AGHAZADEH TABRIZI, Mojgan; Baraldi, Pier Giovanni; Ruggiero, Emanuela; Saponaro, Giulia; Baraldi, Stefania; Poli, Giulio; Tuccinardi, Tiziano; Ravani, Annalisa; Vincenzi, Fabrizio; Borea, Pier Andrea; Varani, Katia
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Contributo in rivista (Pubblicazione in Rivista) |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Vol. 113, No. 1, pp: 11-27, Anno: 2016 |
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Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3’,4’,5’-Trimethoxyphenyl)-2-Aryl-1H-Imidazole
Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; AGHAZADEH TABRIZI, Mojgan; Lopez Cara, Carlota; Ferla, Salvatore; Brancale, Andrea; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Basso, Giuseppe; Viola, Giampietro .
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Contributo in rivista (Pubblicazione in Rivista) |
SCIENTIFIC REPORTS
Vol. 6, No. 1, pp: 26602-1-26602-17, Anno: 2016 |
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Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation
Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Lopez Cara, Carlota; Rondanin, Riccardo; Simoni, Daniele; Hamel, Ernest; Grimaudo, Stefania; Pipitone, Rosaria Maria; Meli, Maria; Tolomeo, Manlio
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Contributo in rivista (Pubblicazione in Rivista) |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Vol. 108, No. 1, pp: 39-52, Anno: 2016 |
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Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety
Vincenzi, Fabrizio; Ravani, Annalisa; Pasquini, Silvia; Merighi, Stefania; Gessi, Stefania; Romagnoli, Romeo; Baraldi, Pier Giovanni; Borea, Pier Andrea; Varani, Katia
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Contributo in rivista (Pubblicazione in Rivista) |
NEUROPHARMACOLOGY
Vol. 111, No. 1, pp: 283-292, Anno: 2016 |
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Medicinal chemistry, pharmacology, and potential therapeutic benefits of cannabinoid CB2receptor agonists
AGHAZADEH TABRIZI, Mojgan; Baraldi, Pier Giovanni; Borea, Pier Andrea; Varani, Katia
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Contributo in rivista (Pubblicazione in Rivista) |
CHEMICAL REVIEWS
Vol. 116, No. 2, pp: 519-560, Anno: 2016 |
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Novel anticancer compounds
Balzarini, Jan; Dehaen, Win; Thomas, Joice; Liekens, Sandra; Romagnoli, Romeo; Baraldi, Pier Giovanni
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Brevetto |
Anno: 2015 |
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One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists
Baraldi, Pier Giovanni; Baraldi, Stefania; Saponaro, Giulia; AGHAZADEH TABRIZI, Mojgan; Romagnoli, Romeo; Ruggiero, Emanuela; Vincenzi, Fabrizio; Borea, Pier Andrea; Varani, Katia
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Contributo in rivista (Pubblicazione in Rivista) |
JOURNAL OF MEDICINAL CHEMISTRY
Vol. 58, No. 13, pp: 5355-5360, Anno: 2015 |
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Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds
Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Balzarini, Jan; Liekens, Sandra; Estévez, Francisco
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Contributo in rivista (Pubblicazione in Rivista) |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Vol. 101, No. 1, pp: 205-217, Anno: 2015 |
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Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin
Romagnoli, Romeo; Baraldi, Pier Giovanni; Salvador, Maria Kimatrai; Prencipe, Filippo; Lopez Cara, Carlota; Schiaffino Ortega, Santiago; Brancale, Andrea; Hamel, Ernest; Castagliuolo, Ignazio; Mitola, Stefania; Ronca, Roberto; Bortolozzi, Roberta; Porcù, Elena; Basso, Giuseppe; Viola, Giampietro
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Contributo in rivista (Pubblicazione in Rivista) |
JOURNAL OF MEDICINAL CHEMISTRY
Vol. 58, No. 7, pp: 3209-3222, Anno: 2015 |
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Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors
AGHAZADEH TABRIZI, Mojgan; Baraldi, Pier Giovanni; Baraldi, Stefania; Prencipe, Filippo; Preti, Delia; Saponaro, Giulia; Romagnoli, Romeo; Gessi, Stefania; Merighi, Stefania; Stefanelli, Angela; Fazzi, Debora; Borea, Pier Andrea; Maia, Rodolfo C. outo; Romeiro, Nelilma C.; Fraga, Carlos A. M; Barreiro, Eliezer J.
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Contributo in rivista (Pubblicazione in Rivista) |
MEDICINAL CHEMISTRY
Vol. 11, No. 4, pp: 342-353, Anno: 2015 |
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